People living with flaring pouchitis are being sought to take part in a Phase 3 clinical trial for a pouchitis treatment being carried out by pharmaceutical company Atlantic Healthcare.
Pouchitis is a condition which can affect people who have had a J-pouch, a type of surgery which removes the colon and creates a pouch using the end of the small bowel. This is then attached to the anus to pass stools normally. Some people with a J-pouch will develop pouchitis - inflammation (colitis) in the pouch.
Atlantic Healthcare is currently trialling a new enema medication called Alicaforsen to treat pouchitis. It is still under development but so far they have tested the product on over 1,000 patients, with no serious drug-related side effects reported. The company is now looking to recruit patients across the UK, Europe, USA and Canada to take part in a Phase 3 trial. More information about what the trial entails can be found here and here.
The trial is open to pouchitis patients who are currently in a flare and have adequately failed to respond to one or more courses of antibiotics or are unable to use antibiotics in their treatment.
If you are interested in participating, click here to fill out a form requesting further information from Atlantic Healthcare. Following a request for information you will be connected to the most convenient study centre. Please note, that participation in the study would require a referral (e.g. from GP or gastroenterologist), and that full participation would be at the discretion of the receiving gastroenterology department, after you have provided fully-informed written consent to take part.
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