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What is inflammatory bowel disease (IBD)?

What is IBD?

Crohn's disease and ulcerative colitis are the two most common forms of inflammatory bowel disease. Rarer forms include lymphocytic colitis and collagenous colitis which tend to be referred to under the single term of microscopic colitis.

IBD is a chronic (lifelong) condition in which parts of the gastrointestinal tract (the gut) become inflamed. Where you get the inflammation depends on which type of IBD you have.

IBD is believed to be an autoimmune condition - in which a person’s immune system attacks healthy cells in the body by mistake.

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What is Crohn’s disease?

In Crohn’s disease the inflammation can be found anywhere from the mouth to the anus. It can affect the entire thickness of the digestive tract and may also skip areas - meaning you could have inflammation near you mouth and also in your small bowel but no where in between.

The type of Crohn’s disease you have will depend on where the inflammation is found. You may be diagnosed with more than one type of Crohn’s disease.

Symptoms vary greatly from person to person depending on the type of Crohn’s disease you have but typical symptoms include abdominal pain, diarrhoea, sickness, fatigue, mouth ulcers, anaemia, loss of appetite and weight loss.

Learn more about Crohn's disease

What is ulcerative colitis (UC)?

In ulcerative colitis the inflammation is found in the colon (large intestine) and the rectum. Small ulcers can develop on the colon’s lining which produce pus and mucus. This can cause abdominal discomfort and frequent emptying of the colon.

The type of UC you are diagnosed with depends on where the inflammation is found.

Symptoms vary greatly from person to person but typical symptoms include diarrhoea (often with blood, mucus and pus), abdomen cramps, fatigue, anaemia, loss of appetite and weight loss.

Learn more about ulcerative colitis

What is microscopic colitis?

As with UC microscopic colitis affects the colon (large intestine) and rectum. However, the inflammation is not as visible as UC and the bowel lining appears normal. When a biopsy is taken inflammation can be seen under a microscope - hence it’s name.

Symptoms vary from the typical symptoms of UC and often result in chronic watery diarrhoea, abdominal pain or discomfort, incontinence, weight loss, fatigue, bloating and wind.

Learn more about microscopic colitis

What is indeterminate colitis?

The name indeterminate colitis is given when it’s unclear if a person has Crohn’s disease or ulcerative colitis (UC). It is thought that around 15% of people with inflammatory bowel disease (IBD) are initially given this diagnosis.

Learn more about indeterminate colitis

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How many people are there with IBD?

IBD is more common than you think and the instance rate is steadily rising, particularly among young people. It is more common in developed nations. It is more common in white people than black people or those of Asian origin. People from an Eastern European Jewish background are most likely to be affected by IBD.

The exact number of how many people are currently diagnosed with IBD around the world is unclear but below are some estimates:

UK: 400,000 people

USA: 3 million people1

Canada: 270,000 people2 - 7 in every 1,000 people (among the highest rate in the world)

Europe: 2.5-3 million people

Australia: 75,000 people

What causes IBD?

It’s not known exactly what causes IBD. Currently it is thought that a number of factors play a part. These could include:

  • The genes you were born with
  • An abnormal reaction of the digestive system to bacteria in the intestine
  • An unknown trigger/s which could include viruses, bacteria, diet, stress or something else in the environment

References

1. Prevalence of Inflammatory Bowel Disease Among Adults Aged 18 years and above - United States, 2015: Weekly / October 28, 2016 / 65(42);1166–1169: James M. Dahlhamer; Emily P. Zammitti; Brian W. Ward; Anne G. Wheaton; Janet B. Croft. https://www.cdc.gov/mmwr/volumes/65/wr/mm6542a3.htm

2. 2018 Impact of Inflammatory Bowel Disease in Canada. https://crohnsandcolitis.ca/Crohns_and_Colitis/documents/reports/2018-Impact-Report-LR.pdf

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